Frequency of mutations in PROP-1 gene in Turkish children with combined pituitary hormone deficiency
Mutations in the prophet of Pit-1 (PROP-1) gene are responsible for most of the cases of combined pituitary hormone deficiencies (CPHD).We performed this study to determine the prevalence of PROP-1 mutations in a group of Turkish children with CPHD.Fifty-three children with the diagnosis of CPHD were included in this study.Clinical data were obtain